• Login
    View Item 
    •   DSpace Home
    • ADU Repository
    • Science
    • Health Science
    • View Item
    •   DSpace Home
    • ADU Repository
    • Science
    • Health Science
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Antioxidant and hepatoprotective effects of Asparagus albus leaves in carbon tetrachloride‐induced liver injury rats

    Thumbnail
    Date
    2018-02
    Type
    Article
    Author
    Beji, Raja Serairi
    Wannes, Wissem Aidi
    Hamdi, Amel
    Tej, Rabeb
    ETAL.
    Metadata
    Show full item record
    Abstract
    The antioxidant and hepatoprotective activities of hot aqueous extract from Asparagus albus (A. albus) leaf against CCl4-induced liver damage in rats were investigated. The total phenolic, flavonoid, and condensed tannin contents of hot aqueous extract from A. albus leaf were determined. The antioxidant activity of hot aqueous extract from A. albus leaf was evaluated using the antioxidant capacity, DPPH free radical-scavenging ability and reducing power assays. Different polyphenolic compounds, namely gallic acid, vanillic acid, 3,4 dimethoxybenzoic acid, catechin, rutin, and quercetin were identified. Oral administration of hot aqueous extract from A. albus leaf to male Wistar, intoxicated with CCl4, demonstrated a significant protective effect by lowering the levels of hepatic marker enzymes (aspartate and lactate transaminases) and by improving the histological architecture of the rat liver. The hot aqueous extract from A. albus leaf attenuated oxidative stress by restoring the activities of superoxide dismutase, catalase, and glutathione peroxidase. This study demonstrated that the hot aqueous extract from A. albus leaf protects rat liver from CCl4-induced injury and suggests a potential therapeutic use for A. albus plant.
    URI
    https://dspace.adu.ac.ae/handle/1/3964
    DOI
    https://doi.org/10.1111/jfbc.12433
    Citation
    Serairi‐Beji, R., Aidi Wannes, W., Hamdi, A., Tej, R., Ksouri, R., Saidani‐Tounsi, M., ... & Karray‐Bouraoui, N. (2018). Antioxidant and hepatoprotective effects of Asparagus albus leaves in carbon tetrachloride‐induced liver injury rats. Journal of Food Biochemistry, 42(1), e12433.
    Collections
    • Health Science

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV
     

     

    Browse

    All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV