In erythroid cells, more than 90% of transferrin-derived iron enters mitochondria where ferrochelatase inserts Fe2+ into protoporphyrin IX. However, the path of iron from endosomes to mitochondrial ferrochelatase remains ...

Hemoglobin synthesis consumes most of the iron that is taken up by cells from plasma transferrin, and this process requires very high expression of transferrin receptors (TfR) at the membranes of erythroid cells. In contrast ...

Thalassemias are a heterogeneous group of red blood cell (RBC) disorders ranging from a clinically severe phenotype requiring lifesaving transfusions (thalassemia major) to a relatively moderate symptomatic disorder, ...

The transferrin receptor (TfR) is a membrane glycoprotein whose only clearly defined function is to mediate cellular uptake of iron (Fe) from a plasma glycoprotein, transferrin. Iron uptake from diferric transferrin (Tf) ...

Normal hemoglobinization of immature red blood cells (RBC) requires iron (Fe) uptake from transferrin (Tf), mediated by Tf receptors (TfR). Following the binding of Fe(III)2-Tf to TfR on the erythroid cell membrane, the ...

In the Nerpio region (Albacete, Spain), endogenous walnut cultivars have been grown since ancient times. None of them has been chemically characterized to valorize them in comparison to commercial varieties. In this work, ...

Genetic and biochemical data have identified at least four viral proteins essential for vaccinia virus (VACV) DNA synthesis: the DNA polymerase E9, its processivity factor (the heterodimer A20/D4) and the primase/helicase ...

The ethanolic extracts from the leaves, pericarps and rhizomes of Asparagus albus L. were investigated for their phytochemical composition, antioxidant (DPPH and FRAP assays), anti-microbial against human pathogenic isolates ...

The protein kinase CDK5 (cyclin-dependent kinase 5) is activated through its association with a cyclin-like protein p35 or p39. In pathological conditions (such as Alzheimer's disease and various other neuropathies), ...

In erythroid cells, more than 90% of transferrin-derived iron enters mitochondria where ferrochelatase inserts Fe2 + into protoporphyrin IX. However, the path of iron from endosomes to mitochondrial ferrochelatase remains ...

Due to the high demand on computation and storage, location based service (LBS) providers prefer to outsource their data and services to powerful cloud service providers (CSPs). However, this mechanism brings three challenging ...

Surface area and the conductivity of the electrode materials are crucial in achieving high desalination performance in capacitive deionization (CDI) applications. In this study, we have successfully fabricated 3D ...

Booming population, higher standard of living, and growing industrialization continue to exert a demand for energy. The continuous and unlimited use of fossil fuels to meet the growing energy demand would deplete the finite ...

Polyvinylidene fluoride (PVDF) membranes play a key role in several industrial applications. Tuning the properties of these membranes enables a sharp selectivity for the target application. The goal of this work is to ...

A method comprising a two-step alkali/acid treatment of poly (vinylidene fluoride) (PVDF) polymer is developed for the fabrication of flat-sheet PVDF membranes functionalized with labile hydroxyl groups. This method involves ...

Lignin forms a recalcitrant structure in lignocellulosic biomass and hence huge amount of enzymes are required for disintegrating it into their subsequent components, like glucose and other by-products. Thus, the pretreatment ...

In this work, we established a simple and effective way of immobilizing CNT onto polyvinylidene fluoride (PVDF) membrane by casting dual-layer membranes. We explored two different methods of dual-layer casting: (i) layer ...

Microalgae technology, if managed properly, has promising roles in solving food-water-energy nexus. The Achilles' heel is, however, to lower the costs associated with cultivation and harvesting. As a favorable technique, ...

This study explored the impact of hydrophobic fumed silica (FS) particles as an inorganic additive in the preparation of polyvinylidenefluoride (PVDF) membranes using the phase inversion technique. PVDF membranes were ...

The establishment of an efficient surface water quality monitoring (WQM) network is a critical component in the assessment, restoration and protection of river water quality. A periodic evaluation of monitoring network is ...

Polyvinylidene fluoride (PVDF) membranes are widely used in membrane industry, especially for membrane bioreactors (MBRs). Many PVDF membranes contain residual polyvinyl pyrrolidone (PVP) that acts as a pore-forming additive. ...

The critical failure mode for membrane distillation (MD) desalination is wetting through the pores of the hydrophobic membrane, which allows the saline solution to leak through and contaminate the permeate. The standard ...

Desalination brine has high salinity and contains various chemical contaminants and its disposal causes a major concern for desalination around the world. Environmentally friendly and economically feasible methods are ...

Research on membrane distillation (MD) experienced a slow growth from the 1970s through 90s but has gained revived interest recently. Despite recent developments, MD still has to overcome several hurdles to pave its path ...

Wood aging is a topic of great interest due to its impact on wood performance and durability as a construction material. Therefore, it is important to develop accurate methods to monitor aging and understand its mechanisms. ...