Show simple item record

dc.contributor.authorAbushammala, Hatem
dc.contributor.authorHashaikeh, Raed
dc.identifier.citationAbushammala, h., & hashaikeh, r. Networked cellulosic gel material as a pharmaceutical excipient.en_US
dc.description.abstractNetworked cellulosic (NC) material was prepared in a gel form via sulfuric acid dissolution and hydrolysis of microcrystalline cellulose (MCC) and then regeneration in ethanol. The regenerated material was utilized as tablet excipient. Prepared tablets have shown interesting properties regarding hardness. Tablets were prepared via slip casting of formulas mixed with different NC gel concentrations. The hardness of prepared tablets was measured using tablet hardness tester. It was noticed that the hardness of the tablets increased over a wide range and up to 420 N. The hardness was mainly controlled by the concentration of the NC gel material. Despite of their high hardness, prepared tablets have shown full drug release capabilities. The new technique to prepare these tablets can be implemented in a continuous process that minimizes the disadvantages of batch processing.en_US
dc.publisherMasdar Institute of Science and Technologyen_US
dc.subjectDrug Deliveryen_US
dc.subjectSulfuric aciden_US
dc.titleNetworked cellulosic gel material as a pharmaceutical excipienten_US

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record